I guess the answer would be a resounding...no!
Really, how would you? You'd need a business license and some awfully good (read...expensive) insurance to do that. And then, would you really want someone else to drive it away?
With the mood of the country with regard to lawsuits these days there is no way on earth I'd let someone take my bus for any amount of money unless I was in the business to do so (then that's a different set of questions). What if the brakes fail; are you willing to face the lawsuit? What if they hit something (it's a really large, strong vehicle) but don't stop and then bring the bus back to you without saying anything? Are you ready for that? Really, I don't mean to be negative but unless you want to make a business of it I would run, not walk, away from a rental situation.
Just my opinion of course...others may disagree...my comments aren't meant to be contentious.