Tires are one place to balance safety with reliability. A blow out can be very exciting or it can be very dangerous depending on when/where it happens.
Retreads are the source of much of the tire litter on freeways. They are regularly used on tractor trailers on the trailers.
Tires are graded as "Steer" and "Drive". Steer tires go on the front and need to specifically rated. Here is an explanation: https://www.bfgoodrichtrucktires.com...tips/position/
Drive tires go in the back.
Either way, a blow out on a motor home can do a tremendous amount of damage to anything near by.
Best solution is not to have a blowout.
You can reduce the risk by not running old tires with defects.
The NTSB recommends removing tires from service after 6 years.
There is a high correlation between old tires and catastrophic failures (blowouts)
Here is a nice power point deck with pictures:
According to one major US insurer - 27% of policyholders from 5 warm weather states accounted for 77% of all claims nationwide and 84% of those claims involved tires over 6 years old.