My mechanic steered me away from cats. Said overall they're good engines but parts and diagnostic equipment are expensive.
The popular engine guide spreadsheet
https://docs.google.com/spreadsheets...gid=1070242319
Lists the 2005 c7 as a yellow. It does have dpf emissions control which can be costly to repair and maintain (at least on Navistar engines, id assume cat wouldn't be any different). I can't speak to a Cummins swap.
The Allison 2000 is a solid tranny. Several of my buses have it. I like the 3000 a little better, but I've never had a problem with any of the 2000s and they're in full length 40 buses. You're probably locked to 5 gears. 6th can be enabled but requires hardware components prior to 2006 1/2 if I recall right. After 2006.5 the hardware is there and just needs a reflash of the tcm. Someone please correct me if I have that wrong.