Since you intend to spend a lot of time on the road going places I think I would pass on this bus for several reasons.
First, the DT466 came in a lot of different HP ratings from as low as 160 HP to as high as 285 HP. A Type 'C' bus with hydraulic brakes is more than likely a route bus that has a low HP engine, the AT545 transmission, and route gearing. So while the engine is a great engine the rest of the package is so-so.
Second, if you are going to spend a lot of time going places you need big HP and highway gears. To retrofit later will cost much more than purchasing a bus that is already set up to go highway speeds and up hills quickly.
Third, if you are going to be traveling a lot that means you will be going through mountains. Air brakes usually have much greater braking surfaces than most hydraulic brakes. More braking surface means less brake fade. Less brake fade means more stopping ability. Also most hydraulic brake equipped vehicles have really poor emergency/parking brakes. All buses made in the last 40-years have spring brakes that apply the rear brakes in case of loss of air or for parking. They will stop the bus and keep it stopped much better than any hand brake. Air brakes also require much less care and feeding when not in use. Brake fluid is hydroscopic (attracts water). Over time that characteristic means water builds up in the brake fluid which reduces the ability of the brake fluid to shed heat and the water tends to rust and corrode the hard parts which will cause the soft parts to fail.
And lastly, you don't mention whether you anticipate a roof raise or not. If you get a high ceiling model you probably won't need to raise the roof. If you get a standard or low ceiling model you will most probably need to raise the roof.
So while the price is attractive you might discover that purchasing a bus 3x-5x as expensive will actually cost you less in the long run.
As always, regardless of price, if it has rust walk away from it!